A New Portal to SuFEx Click Chemistry: a Stable Fluorosulfuryl Imidazolium Salt Emerging as an 'FSO2 ' Donor of Unprecedented Reactivity, Selectivity, and Scope: Sulfuryl fluoride, SO2F2, has been found to derivatize phenols of all kinds of environments, even those in highly polyfunctional molecules. We now report that solid reagent 3-1 delivers the same "F-SO2+" fragment to Nu-H acceptor groups in the substrates. However, triflate salt 3-1 is a far more reactive fluorosulfating agent than SO2F2 and displays selectivity preferences of its own. Moreover, the new azolium triflate reagent reacts once with primary amines and anilines, and stops.
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